Julaine
A collagen-stimulating injectable made from poly-L-lactic acid. Rather than adding instant volume, Julaine encourages your skin to build its own collagen, so firmness and lines improve gradually over the following months.
What it is
Not a filler. A collagen stimulator.
Julaine is an injectable made from poly-L-lactic acid (PLLA), a biocompatible, biodegradable material with a long history of use in medicine. It is developed and manufactured in Sweden by Nordberg Medical, and is a CE-marked medical device.
Hyaluronic acid fillers add volume the moment they are placed. Julaine works differently: it prompts the skin to produce more of its own collagen, so any change builds slowly and quietly over the months after treatment. It suits people who would like firmer, better-supported skin without an obvious change to their features.
Collagen production slows with age, and skin gradually loses some of its structure and bounce. Julaine is designed to encourage new collagen in the treated area.
Loss of firmnessJulaine's CE-marked indication is the correction of shallow to deep nasolabial folds, softening them gradually as collagen builds.
Nasolabial foldsBecause the change develops over months, it tends to look like your own skin rather than something added.
Gradual, natural changeWhere volume has genuinely been lost, a hyaluronic acid filler may be the better answer. Your consultation looks at which approach, or combination, suits your face.
Choosing the right approachHow it works
Gradual by design.
Julaine is based on Nordberg Medical's LASYNPRO technology: fine PLLA microspheres that are reconstituted with sterile water before treatment and placed in the deeper layers of the skin.
The microspheres are injected with a fine needle or cannula into the areas agreed at your consultation.
The microspheres signal the skin's fibroblasts, the cells that make collagen, to increase production.
New collagen forms gradually over the weeks and months after each session, supporting firmness and softening lines.
PLLA is biodegradable. The body breaks it down naturally over time, while the collagen it helped to stimulate remains for a period.
What it can help with
Support where the skin has softened.
Nose-to-mouth lines
The area Julaine is CE-marked for: gradually softening shallow to deep folds running from the nose to the corners of the mouth.
Midface support
Where the cheeks have lost some firmness, stimulating collagen can help the skin look better supported.
Jawline and jowl area
Early softening along the lower face may benefit from improved skin firmness, assessed in the context of your whole face.
Firmness and texture
As collagen builds, skin can feel firmer and look smoother, with results that develop gradually.
Decided at your consultation
Nothing is injected before your face is assessed as a whole. Whether Julaine suits you, which areas to treat and how many sessions you may need are agreed with you first.
Your consultant
Led by Dr Jinah Yoo.
Dr Jinah Yoo
MBChB FRCP · Consultant Dermatologist · FounderDr Jinah Yoo is a Korean UK-trained consultant dermatologist who is the founder and medical director of Dr Jinah Yoo Dermatology. Dr Yoo has completed intensive dermatology training and developed special interest in cosmetic dermatology, hyperpigmentary disorders and skin lymphoma.
She attended numerous observerships at the World's leading pigment/cosmetic dermatology clinics in USA, Singapore and South Korea and established the first NHS-based hyperpigmentation service at Queen Elizabeth Hospital in 2018.
- GMC-registered consultant dermatologist
- Fellow of the Royal College of Physicians (FRCP)
- Distinction in MSc, University of Manchester
- MSc project work on facial hyperpigmentation
Your journey, step by step
What to expect.
Personalised 1:1 consultation
Your face, skin quality and medical history are assessed, and Dr Yoo explains whether Julaine is likely to suit you or whether another approach would serve you better. If you go ahead, your treatment plan and realistic expectations are agreed before anything is injected.
You commit to nothing at this stageTreatment sessions
Julaine is usually given as a short course, typically two to three sessions spaced a few weeks apart, although the number of sessions depends on your skin and goals. Most people find the injections well tolerated.
Your plan is agreed at consultationBack to your day
Most people return to their usual routine soon after treatment. Some redness, swelling, tenderness or bruising at the injection sites is common and usually settles within a few days. Any early fullness is temporary and fades as the swelling settles.
Minimal downtime for most peopleResults develop gradually
Collagen builds slowly, so changes are usually noticed over several weeks, with the fuller effect typically seen around three months after a course is completed. Results vary from person to person.
How long it lasts
Results are long-lasting but not permanent. Published reports and product information describe results lasting a year or more in many people, depending on age, skin condition and lifestyle. Maintenance sessions are usually recommended to sustain them.
Aftercare
Looking after your skin.
Advice on whether and how to massage the treated area varies with the areas treated, so follow the specific aftercare instructions you are given.
Any swelling, redness, tenderness or bruising at the injection sites should settle within a few days.
Avoid saunas, steam rooms, extreme temperatures and strong sun exposure for a few days after treatment.
Small bumps under the skin can occasionally develop after PLLA treatment. Contact the clinic if anything feels unusual, persists or worries you.
The clinic
45 Albemarle Street, Mayfair.
Suitability
Is Julaine for you?
- Early to moderate loss of skin firmness
- Nasolabial folds you would like to soften gradually
- A preference for subtle change that develops over time
- Happy to commit to a short course of sessions
- Wanting an immediate change in volume, where filler may suit better
- Advanced laxity, where lifting or surgery may be the honest answer
- Pregnancy or breastfeeding
- Active skin infection, inflammation or cold sores in the treatment area
- Autoimmune conditions or a history of keloid or raised scarring
- Allergy to any component, blood-thinning medication or bleeding disorders
Questions
Asked before booking.
Hyaluronic acid fillers are gels that add volume as soon as they are injected. Julaine is a poly-L-lactic acid collagen stimulator: it encourages your skin to produce its own collagen, so the change is gradual rather than immediate. The two can have different roles, and Dr Yoo will advise which is appropriate for you.
Because the effect depends on new collagen forming, changes are usually noticed over several weeks, with the fuller effect typically seen around three months after a course is completed. Results vary from person to person.
Julaine is usually given as a short course, typically two to three sessions a few weeks apart. The number of sessions you need depends on your skin and goals, and is agreed at your consultation.
Results are long-lasting but not permanent. Published reports and product information describe results lasting a year or more in many people, depending on age, skin condition and lifestyle, and maintenance sessions are usually recommended.
Most people find the treatment well tolerated, with some mild discomfort during the injections. Ways to keep you comfortable are discussed at your consultation.
Redness, swelling, tenderness and bruising at the injection sites are common and usually settle within a few days. Small bumps under the skin can occasionally occur. As with any injectable, there are rarer risks, which Dr Yoo will explain in full before you decide.
Yes. Julaine is a CE-marked medical device, manufactured in Sweden by Nordberg Medical. Like any injectable, it should only be administered by a qualified medical practitioner after a proper consultation.
Next step
Collagen, rebuilt at your skin's pace.
A personalised 1:1 consultation first, with your course, areas and realistic expectations agreed before any treatment begins.
