The Journal◇Ageing & Lifting

Profhilo in London: How This Injectable Skin Booster Works

2 Nov 2026◆5 min read

Clinician giving an injectable skin treatment along a patient's jawline in clinic

Profhilo has become one of the most talked-about injectable treatments in London, valued for improving skin quality rather than changing the shape of the face. It is often described as a skin booster, but it works a little differently from both traditional boosters and dermal fillers, which is worth understanding before you book.

At our Mayfair clinic, Profhilo is carried out by consultant dermatologist Dr Jinah Yoo as part of a considered, doctor-led approach to skin health. This guide explains what Profhilo is, how it works, and what it can realistically do for your skin.

What Is Profhilo?

Profhilo is an injectable treatment made from a high concentration of hyaluronic acid, a substance that occurs naturally in the skin and helps it hold moisture. Unlike dermal fillers, it is not designed to add volume or contour the face.

Instead, Profhilo is what is known as a bio-remodelling treatment. Once injected, it spreads through the skin and works to improve hydration and firmness from within, supporting better overall skin quality.

How Profhilo Works

Profhilo delivers a large amount of hyaluronic acid into the skin, where it does two main things. First, it deeply hydrates, which improves the look and feel of the skin. Second, it stimulates the skin to produce more of its own collagen and elastin, the proteins that keep skin firm and supple.

This combination is why Profhilo is described as bio-remodelling rather than filling. Over the weeks following treatment, the skin gradually looks more hydrated, smoother and firmer, with an improvement in overall quality rather than a change in shape.

How Profhilo Differs from Fillers and Skin Boosters

This is the point that causes the most confusion, so it is worth being clear:

  • Profhilo is not a filler – it does not add volume or contour. Dermal fillers are used to restore volume and shape, which is a different goal.
  • Profhilo is a type of skin booster – but a particularly spreadable, bio-remodelling one that works across a wider area rather than just where it is placed.
  • It targets skin quality – hydration, firmness and texture, rather than lines or volume loss specifically.

Understanding this helps set the right expectations. Profhilo improves the canvas of the skin, and it can sit alongside other treatments such as skin boosters within a wider plan.

What Profhilo Treats

Profhilo is mainly used to improve skin that has started to lose firmness and hydration. It can help with:

  • Skin laxity – early loss of firmness, particularly on the face and neck.
  • Crepey skin – fine, papery texture, common on the neck and around the lower face.
  • Dull, dehydrated skin – improving radiance and smoothness.
  • Other areas – the neck, hands and décolletage can also be treated.

It is not intended to lift sagging skin significantly or to replace volume, which is where other treatments may be more appropriate.

Who It Suits

Profhilo suits people who want to improve the quality and firmness of their skin rather than change its shape. It is often chosen by those noticing the first signs of laxity or dehydration, but it can benefit a wide range of ages.

There is no upper age limit. Older skin can respond well, although the degree of improvement depends on the overall condition of the skin. A consultation helps establish whether Profhilo is the right choice for your goals.

Combining Profhilo with Other Treatments

Because Profhilo improves the quality of the skin rather than its shape, it often works well alongside other treatments within a wider plan. It can complement treatments that address volume or lines, while Profhilo focuses on hydration and firmness.

Other regenerative injectables, such as salmon polynucleotide treatment, work in related but different ways, and a consultation helps decide which is most appropriate for your skin. In some cases a combination gives the most rounded result, with each treatment doing a specific job rather than overlapping.

What to Expect

The standard approach is usually two treatment sessions about four weeks apart, followed by maintenance every six months or so. Profhilo is injected at a small number of precise points, from which it spreads through the skin.

Treatment is quick, and downtime is minimal. Small raised bumps at the injection points are normal and usually settle within a day. Results develop gradually over the following weeks as hydration improves and collagen stimulation takes effect.

Risks and Considerations

Profhilo is generally well tolerated, but as with any injectable treatment there are a few considerations:

  • Bruising and swelling – possible at the injection points and usually short-lived.
  • Temporary bumps – the small raised areas after treatment settle quickly.
  • Realistic expectations – Profhilo improves skin quality and firmness, but it does not replace volume or provide a surgical lift.

Having treatment carried out by an experienced medical practitioner helps ensure it is both safe and appropriate for your skin.

The Dr Jinah Yoo Approach

Profhilo gives its best results as part of a considered plan rather than a standalone fix. As a GMC-registered consultant dermatologist, Dr Jinah Yoo approaches it accordingly:

  • Your skin is assessed to confirm Profhilo suits your goals.
  • It is recommended where skin quality, not volume, is the concern.
  • Treatment is doctor-led and tailored to your skin.
  • Honest advice is given about what Profhilo can and cannot achieve.

You can read more about Dr Jinah Yoo and her approach to injectable skin treatments.

Frequently Asked Questions

How much does Profhilo cost in the UK?

Cost depends on the number of sessions and areas treated, and Profhilo is usually started as a short course followed by maintenance. Because plans are tailored, a clear price is provided after your consultation, once your skin and goals have been assessed.

Is Profhilo worth the money?

For those wanting to improve skin hydration, firmness and overall quality, many people find Profhilo worthwhile, particularly when maintained over time. Whether it is right for you depends on your goals, since Profhilo improves skin quality rather than adding volume or lifting.

Is anything better than Profhilo?

There is no single best treatment, because the right choice depends on your skin and what you want to achieve. Other bio-remodelling and skin booster treatments, including polynucleotide injections, may suit some people better. An assessment helps identify the most appropriate option for you.

Is 60 too old for Profhilo?

No. There is no upper age limit for Profhilo, and older skin can respond well to it. The degree of improvement depends on the condition of your skin rather than your age, which is something your dermatologist will discuss honestly at consultation.

Does Profhilo hurt?

Profhilo is injected at only a few points, and most people find it well tolerated. You may feel a brief sting as the product is placed, and numbing can be used for comfort where appropriate. Any small bumps at the injection sites usually settle within a day.

Arranging a Consultation

If you would like firmer, more hydrated and better-quality skin, Profhilo may be worth considering. You are welcome to book a consultation with Dr Jinah Yoo at our Mayfair clinic.

Next step

Book a consultation to discover a tailored skin treatment plan.

Every plan starts with a consultant-led diagnosis in Mayfair.

The Dr Jinah Yoo sign outside the clinic on Albemarle Street