Salmon Polynucleotides
Salmon PN is DNA extracted from salmon, closely resembling human DNA. Injected into the skin, it stimulates healing and regeneration, improving hydration, sensitive skin and overall rejuvenation.
How it works
DNA that your skin recognises.
Polynucleotide injections introduce salmon-derived DNA fragments, shown in multiple clinical trials to enhance the skin's regenerative properties, particularly in sensitive skin. The polynucleotides boost collagen production, directly improving the skin's structure and supporting better elasticity. Over time, the treatment strengthens the skin's resilience against environmental factors and addresses sagging and fine lines.
Salmon PN is closely similar to human DNA, which is why it is tolerated where stronger treatments are not, and why its calming, anti-inflammatory effect suits sensitive and reactive skin.
Sensitive skinPolynucleotides act at a cellular level, improving the skin's own ability to regenerate, effective for dark eye circles, open pores and fine lines where hydration alone falls short.
Under-eye & fine linesPN injections help smooth the appearance of acne scars and minimise enlarged pores, giving a more even and refined skin surface.
Acne scars & poresBy stimulating collagen and elastin, PN reduces fine lines and supports elasticity, a non-surgical route to sagging and early ageing, built on your own tissue.
Sagging & ageingWho can benefit
Recommended for.
- Those wanting a non-surgical solution for anti-ageing, sagging or fine lines
- Sensitive skin that requires a gentle, safe approach
- Anyone seeking long-term improvement in texture, elasticity and hydration
- Acne scars, enlarged pores or skin tone irregularities
- Treating multiple areas, including the face and neck
- Active skin infection: treatment must wait until it has healed
- Diabetes or other specific health conditions, which should be confirmed with your healthcare provider
- Known allergy to fish or salmon-derived products
- Pregnancy or breastfeeding
- Volume loss as the main concern: filler may suit better
“Polynucleotides work at the level of the cell, not the surface. That is what makes them the right answer for skin too sensitive to tolerate anything aggressive.”
Treatment benefits
What salmon PN does.
Skin tissue regeneration
The polynucleotides in salmon DNA injections stimulate natural skin cell regeneration, promoting youthful, resilient skin.
Anti-inflammatory effects
Known for its calming, anti-inflammatory properties, an excellent choice for sensitive skin, and for reducing redness or irritation.
Acne scar improvement
Helps smooth and improve the appearance of acne scars, giving the skin a more even and refined texture.
Uneven skin tone correction
Targets uneven pigmentation and helps achieve a balanced, even skin tone.
Enlarged pore reduction
Minimises the appearance of enlarged pores, resulting in smoother, more refined skin texture.
Skin rejuvenation
By enhancing hydration and collagen production, the treatment restores skin vitality and contributes to an overall rejuvenated appearance.
Lines and wrinkles reduced
Stimulates collagen and elastin, reducing the appearance of fine lines and wrinkles for a smoother complexion.
Decided at your diagnosis
Areas, session count and whether PN is combined with other skinboosters all follow from your consultation, written down before treatment begins.
Why our PN injections
Rejuran, then tailored.
At Dr Jinah Yoo we use Rejuran, one of the original and most trusted polynucleotide injections, and a leading treatment in Korea for over ten years. Derived from high-quality salmon DNA, it is known for its regenerative properties, promoting skin healing, hydration and overall rejuvenation.
What sets Dr Jinah Yoo PN apart is the combination of Rejuran with other advanced skinboosters, tailored to enhance collagen production, improve texture and address a wide range of concerns at once. That customised approach is what delivers optimal, long-lasting results with minimal downtime.
Your consultant
Injected by a consultant dermatologist.
Dr Jinah Yoo
MBChB FRCP · Consultant Dermatologist · FounderDr Yoo is a Korean, UK-trained consultant dermatologist and the founder and medical director of Dr Jinah Yoo Dermatology, with special interests in cosmetic dermatology, hyperpigmentary disorders and skin lymphoma. She has completed two Master's degrees alongside her medical training, including an MSc awarded with Distinction at the University of Manchester.
Rejuran has been used in Korea for over a decade. Dr Yoo works with it as it is used there, combined with the boosters that suit each individual skin.
- GMC-registered consultant dermatologist
- Fellow of the Royal College of Physicians (FRCP)
- Korean regenerative protocols, delivered in London
- PN combined with skinboosters, lasers and RF where appropriate
Your journey, step by step
What actually happens.
Consultation & skin analysis
Your skin is examined and the concern identified: sensitivity, scarring, pores, tone or early ageing. A personalised plan is then created, including whether PN alone or a combination with other boosters is right for you.
You commit to nothing at this stageThe treatment
The session includes cleansing and preparation of the injection site, and local anaesthetic may be applied to ensure minimal discomfort. The injections are then placed across the treatment area, and you can return to daily life almost immediately afterwards.
Straightforward, with little downtimeThe course
Some patients see improvement after a single session. For optimal, long-lasting results, a series of treatments spaced four to six weeks apart may be recommended, the exact number set out in your personalised plan.
Progress reviewed at each visitThe result, and maintenance
Results can last up to six months as the treatment stimulates natural collagen production and tissue repair. Studies suggest that with routine treatment, elasticity, texture and brightness improve progressively.
Aftercare
For the best outcome.
Avoid make-up and strenuous activities for twenty-four hours to allow the skin to settle.
Keep the treated area hydrated and avoid sun exposure, as the skin may be more sensitive.
Minor swelling, bruising or tenderness may appear at the injection site, and should subside within a few days.
Salmon PN treatments are safe with minimal side effects, owing to their similarity to human DNA.
The clinic
45 Albemarle Street, Mayfair.
Questions
Asked before booking.
Most skin boosters primarily use hyaluronic acid. Salmon DNA treatments use polynucleotides, which act at a cellular level to enhance the skin's natural ability to regenerate, helping tackle dark eye circles, open pores and fine lines effectively.
Results can last up to six months, as the treatment stimulates natural collagen production and tissue repair. Studies suggest that with routine treatments, elasticity, texture and brightness improve progressively.
Some patients see improvement after a single session. For optimal, long-lasting results a series of treatments spaced four to six weeks apart may be recommended. Our specialists create a personalised plan based on your skin.
Yes, generally suitable for all skin types, including sensitive and acne-prone skin. A consultation is still advisable to confirm it is right for your specific concerns and conditions.
Salmon polynucleotide treatments are safe and have minimal side effects due to their similarity to human DNA. Minor swelling, bruising or tenderness may appear at the injection site but should subside within a few days.
Yes. PN injections complement other treatments including glycolic acid peels, various skinboosters and treatments for acne-prone skin, allowing enlarged pores, uneven tone and fine lines to be addressed together.
No. It is essential to wait until the skin condition has healed, to prevent complications and ensure the treatment is effective. Consult a specialist before proceeding.
Diabetic patients, and those with other specific health conditions, should consult their healthcare provider before treatment to confirm suitability. While salmon DNA therapy is generally safe, it is best confirmed against individual health needs.
Yes. PN injections improve hydration by enhancing the skin's ability to retain moisture, leaving it smoother and plumper, and stimulate collagen and elastin production to improve elasticity, helping reduce sagging and fine lines.
Next step
Regeneration, on your skin's own terms.
Book a consultation and your skin is examined first, then the protocol, sessions and cost agreed in writing.
